Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Surgical Pathology ClinicsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Pathology and genetics of phaeochromocytoma and paraganglioma.Histopathology. 2018; 72: 97-105
- Succinate dehydrogenase (SDH) and mitochondrial driven neoplasia.Pathology. 2012; 44: 285-292
- Review of Pediatric Pheochromocytoma and Paraganglioma.Front Pediatr. 2017; 5: 155
- Succinate dehydrogenase (SDH)-deficient neoplasia.Histopathology. 2018; 72: 106-116
- Pseudohypoxic pheochromocytomas and paragangliomas dominate in children.Pediatr Blood Cancer. 2021; 68: e28981
- Pheochromocytoma and Paraganglioma in Children and Adolescents: Experience of the French Society of Pediatric Oncology (SFCE).J Endocr Soc. 2020; 4: bvaa039
- Metastatic pheochromocytoma/paraganglioma related to primary tumor development in childhood or adolescence: significant link to SDHB mutations.J Clin Oncol. 2011; 29: 4137-4142
- Mitochondrial tumour suppressors: a genetic and biochemical update.Nat Rev Cancer. 2005; 5: 857-866
- Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.Oncogene. 2006; 25: 4675-4682
- An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.Lancet Oncol. 2009; 10: 764-771
- Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.Hum Mol Genet. 2005; 14: 2231-2239
- TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2alpha-Driven Mesenchymal Transition.Cell Rep. 2020; 30: 4551-4566.e7
- Succinate dehydrogenase deficiency is rare in pituitary adenomas.Am J Surg Pathol. 2014; 38: 560-566
- Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad.Endocr Relat Cancer. 2014; 21: 567-577
- Recurrent epimutation of SDHC in gastrointestinal stromal tumors.Sci Transl Med. 2014; 6: 268ra177
- SDHC Methylation Pattern in Patients With Carney Triad.Appl Immunohistochem Mol Morphol. 2021; 29: 599-605
- A Full Phenotype of Paraganglioma Linked to a Germline SDHB Mosaic Mutation.J Clin Endocrinol Metab. 2019; 104: 3362-3366
- Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types.Am J Surg Pathol. 2010; 34: 636-644
- Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age.Am J Surg Pathol. 2011; 35: 1712-1721
- Expanding the clinicopathological spectrum of succinate dehydrogenase-deficient renal cell carcinoma with a focus on variant morphologies: a study of 62 new tumors in 59 patients.Mod Pathol. 2021; 35: 836-849
- Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma.Am J Surg Pathol. 2007; 31: 1844-1853
- Loss of succinate dehydrogenase B immunohistochemical expression distinguishes pulmonary chondromas from hamartomas.Histopathology. 2019; 75: 825-832
- 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5.Endocr Relat Cancer. 2015; 22: T91-T103
- Succinate Dehydrogenase Complex: An Updated Review.Arch Pathol Lab Med. 2018; 142: 1564-1570
- Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency.Nat Genet. 1995; 11: 144-149
- Loss of SDHA expression identifies SDHA mutations in succinate dehydrogenase-deficient gastrointestinal stromal tumors.Am J Surg Pathol. 2013; 37: 226-233
- SDHA is a tumor suppressor gene causing paraganglioma.Hum Mol Genet. 2010; 19: 3011-3020
- Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes.J Clin Endocrinol Metab. 2006; 91: 827-836
- Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas.Cancer Res. 2003; 63: 5615-5621
- High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing.J Clin Endocrinol Metab. 2006; 91: 4505-4509
- Clinical presentations, biochemical phenotypes, and genotype-phenotype correlations in patients with succinate dehydrogenase subunit B-associated pheochromocytomas and paragangliomas.J Clin Endocrinol Metab. 2007; 92: 779-786
- Are we overestimating the penetrance of mutations in SDHB?.Hum Mutat. 2010; 31: 761-762
- Mitochondrial complex II and genomic imprinting in inheritance of paraganglioma tumors.Biochim Biophys Acta. 2013; 1827: 573-577
- Maternal transmission of symptomatic disease with SDHD mutation: fact or fiction?.J Clin Endocrinol Metab. 2008; 93: 1573-1575
- Genomic imprinting: recognition and marking of imprinted loci.Curr Opin Genet Dev. 2012; 22: 72-78
- SDHAF2 (PGL2-SDH5) and hereditary head and neck paraganglioma.Clin Cancer Res. 2011; 17: 247-254
- Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations.JAMA. 2004; 292: 943-951
- Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD.Hum Mutat. 2010; 31: 41-51
- Bayesian approach to determining penetrance of pathogenic SDH variants.J Med Genet. 2018; 55: 729-734
- Pathogenicity and Penetrance of Germline SDHA Variants in Pheochromocytoma and Paraganglioma (PPGL).J Endocr Soc. 2018; 2: 806-816
- Carbonic anhydrase 9 immunohistochemistry as a tool to predict or validate germline and somatic VHL mutations in pheochromocytoma and paraganglioma-a retrospective and prospective study.Mod Pathol. 2020; 33: 57-64
- Immunohistochemical expression of carbonic anhydrase 9, glucose transporter 1, and paired box 8 in von Hippel-Lindau disease-related lesions.Hum Pathol. 2022; 123: 93-101
- Urinary Bladder Paragangliomas: Analysis of Succinate Dehydrogenase and Outcome.Endocr Pathol. 2016; 27: 243-252
- Incidence of succinate dehydrogenase and fumarate hydratase-deficient renal cell carcinoma based on immunohistochemical screening with SDHA/SDHB and FH/2SC.Hum Pathol. 2019; 91: 114-122
- Immunohistochemical screening for the diagnosis of succinate dehydrogenase-deficient renal cell carcinoma and fumarate hydratase-deficient renal cell carcinoma.Ann Transl Med. 2019; 7: S324
- Multiple Endocrine Tumors Associated with Germline MAX Mutations: Multiple Endocrine Neoplasia Type 5?.J Clin Endocrinol Metab. 2021; 106: 1163-1182
- Old, New, and Emerging Immunohistochemical Markers in Pheochromocytoma and Paraganglioma.Endocr Pathol. 2018; 29: 169-175
- Complex MAX Rearrangement in a Family With Malignant Pheochromocytoma, Renal Oncocytoma, and Erythrocytosis.J Clin Endocrinol Metab. 2016; 101: 453-460
- SDHA immunohistochemistry detects germline SDHA gene mutations in apparently sporadic paragangliomas and pheochromocytomas.J Clin Endocrinol Metab. 2011; 96: E1472-E1476
- Loss of expression of SDHA predicts SDHA mutations in gastrointestinal stromal tumors.Mod Pathol. 2013; 26: 289-294
- Molecular imaging and theranostic approaches in pheochromocytoma and paraganglioma.Cell Tissue Res. 2018; 372: 393-401
- Peptide receptor radionuclide therapy in the management of advanced pheochromocytoma and paraganglioma: A systematic review and meta-analysis.Clin Endocrinol (Oxf). 2019; 91: 718-727
- The Diagnosis and Clinical Significance of Paragangliomas in Unusual Locations.J Clin Med. 2018; 7
- Head and neck paragangliomas: A two-decade institutional experience and algorithm for management.Laryngoscope Investig Otolaryngol. 2017; 2: 380-389
- Incidence of pheochromocytoma and sympathetic paraganglioma in the Netherlands: A nationwide study and systematic review.Eur J Intern Med. 2018; 51: 68-73
- Benign paragangliomas: clinical presentation and treatment outcomes in 236 patients.J Clin Endocrinol Metab. 2001; 86: 5210-5216
- Biochemical and clinical manifestations of dopamine-producing paragangliomas: utility of plasma methoxytyramine.J Clin Endocrinol Metab. 2005; 90: 2068-2075
- Dopamine excess in patients with head and neck paragangliomas.Anticancer Res. 2010; 30: 5153-5158
- Images in clinical medicine. Paraganglioma of the middle ear.N Engl J Med. 1995; 333: 1677
- Vagal paraganglioma: a review of 46 patients treated during a 20-year period.Arch Otolaryngol Head Neck Surg. 1998; 124: 1133-1140
- Head and neck paragangliomas: clinical and molecular genetic classification.Clinics (Sao Paulo). 2012; 67: 19-28
- Altitude is a phenotypic modifier in hereditary paraganglioma type 1: evidence for an oxygen-sensing defect.Hum Genet. 2003; 113: 228-237
- Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma.Clin Cancer Res. 2010; 16: 4148-4154
- Carotid body tumour associated with cyanotic heart disease.BMJ Case Rep. 2016; 2016
- Insulinoma-associated Protein 1 (INSM1) in Thoracic Tumors is Less Sensitive but More Specific Compared With Synaptophysin, Chromogranin A, and CD56.Appl Immunohistochem Mol Morphol. 2020; 28: 237-242
- The Diagnostic Dilemma of GATA3 Immunohistochemistry in Pheochromocytoma and Paraganglioma.Endocr Pathol. 2020; 31: 95-100
- Images in Endocrine Pathology: Progressive Loss of Sustentacular Cells in a Case of Recurrent Jugulotympanic Paraganglioma over a Span of 5 years.Endocr Pathol. 2020; 31: 310-314
- Clinical impact of somatostatin receptor scintigraphy in the management of paragangliomas of the head and neck.J Nucl Med. 2003; 44: 1767-1774
- Familial cervical paragangliomas with lymph node metastasis expressing somatostatin receptor type 2A.Endocr Pathol. 2010; 21: 139-143
- Application of GATA 3 and TTF-1 in differentiating parathyroid and thyroid nodules on cytology specimens.Diagn Cytopathol. 2020; 48: 128-137
- Utility of GATA-3 Expression in the Analysis of Pituitary Neuroendocrine Tumour (PitNET) Transcription Factors.Endocr Pathol. 2020; 31: 150-155
- Frequency and extent of cytokeratin expression in paraganglioma: an immunohistochemical study of 60 cases from 5 anatomic sites and review of the literature.Hum Pathol. 2019; 93: 16-22
- Immunohistochemical Biomarkers in Thyroid Pathology.Endocr Pathol. 2018; 29: 91-112
- Paragangliomas of the Head and Neck: An Overview from Diagnosis to Genetics.Head Neck Pathol. 2017; 11: 278-287
- The presence of SDHB mutations should modify surgical indications for carotid body paragangliomas.Ann Surg. 2014; 260: 158-162
- Characterization of Malignant Head and Neck Paragangliomas at a Single Institution Across Multiple Decades.JAMA Otolaryngol Head Neck Surg. 2019; 145: 641-646
- Characteristics and Outcomes of Metastatic Sdhb and Sporadic Pheochromocytoma/Paraganglioma: An National Institutes of Health Study.Endocr Pract. 2016; 22: 302-314
- Incidence and Clinical Presentation of Pheochromocytoma and Sympathetic Paraganglioma: A Population-based Study.J Clin Endocrinol Metab. 2021; 106: e2251-e2261
- Pediatric patients with pheochromocytoma and paraganglioma should have routine preoperative genetic testing for common susceptibility genes in addition to imaging to detect extra-adrenal and metastatic tumors.Surgery. 2017; 161: 220-227
- Characteristics of Pediatric vs Adult Pheochromocytomas and Paragangliomas.J Clin Endocrinol Metab. 2017; 102: 1122-1132
- ACTH-producing pheochromocytoma: clinical considerations and concise review of the literature.Eur J Intern Med. 2009; 20: 682-685
- Cushing's syndrome due to ectopic CRH secretion by adrenal pheochromocytoma accompanied by renal infarction.Exp Clin Endocrinol Diabetes. 2006; 114: 444-447
- Watery diarrhoea and hypokalaemia associated with a phaeochromocytoma.Postgrad Med J. 1975; 51: 416-419
- Metabologenomics of Phaeochromocytoma and Paraganglioma: An Integrated Approach for Personalised Biochemical and Genetic Testing.Clin Biochem Rev. 2017; 38: 69-100
- Primary Renal Paragangliomas and Renal Neoplasia Associated with Pheochromocytoma/Paraganglioma: Analysis of von Hippel-Lindau (VHL), Succinate Dehydrogenase (SDHX) and Transmembrane Protein 127 (TMEM127).Endocr Pathol. 2017; 28: 253-268
- Genetic stratification of inherited and sporadic phaeochromocytoma and paraganglioma: implications for precision medicine.Hum Mol Genet. 2020; 29: R128-R137
- Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.Cancer Cell. 2017; 31: 181-193
- Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma.Cell Tissue Res. 2018; 372: 367-378
- A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.Plos Genet. 2005; 1: 72-80
- Sino-European Differences in the Genetic Landscape and Clinical Presentation of Pheochromocytoma and Paraganglioma.J Clin Endocrinol Metab. 2020; : 105
- Dopamine beta-hydroxylase: An Essential and Optimal Immunohistochemical Marker for Pheochromocytoma and Sympathetic Paraganglioma.Endocr Pathol. 2021; 32: 258-261
- Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene.J Clin Endocrinol Metab. 2008; 93: 4826-4832
- Immunohistochemical Biomarkers of Adrenal Cortical Neoplasms.Endocr Pathol. 2018; 29: 137-149
- COPPS, a composite score integrating pathological features, PS100 and SDHB losses, predicts the risk of metastasis and progression-free survival in pheochromocytomas/paragangliomas.Virchows Arch. 2019; 474: 721-734
- Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma.Endocr Relat Cancer. 2014; 21: 405-414
- Validation of pathological grading systems for predicting metastatic potential in pheochromocytoma and paraganglioma.PLoS One. 2017; 12: e0187398
- Pheochromocytoma of the Adrenal gland Scaled Score (PASS) to separate benign from malignant neoplasms: a clinicopathologic and immunophenotypic study of 100 cases.Am J Surg Pathol. 2002; 26: 551-566
Article info
Footnotes
Sources of Support: None.
Identification
Copyright
© 2023 Elsevier Inc. All rights reserved.
